Immunopathogenesis of HIV Infection: The Complex Role of the Immune System in Disease Development and Control (doc)

Human immunodeficiency virus (HIV) infection remains a global challenge in public
health, and a deeper understanding of its immunopathogenesis is essential for the
development of more effective therapies and more efficient vaccines. the complexity of the
interaction between HIV and the human immune system leads to a diverse course of the
disease. Explanation of the main role of immune system components in detecting and
responding to HIV infection, with special emphasis on the role of CD4+ T cells and the
evation mechanisms applied by the HIV virus to avoid destruction by the immune system
as well as the impact of HIV infection on dendritic cells, which play an important role in
antigen presentation and initiation of immune response. We discuss how HIV utilizes
dendritic cells for more efficient dissemination in the body and its impact on specific
immunity. By integrating an in-depth understanding of the interaction between HIV and
the immune system, this article aims to provide comprehensive insight into the
immunopathogenesis of HIV infection and highlight future research directions to combat
the disease. A better understanding of these complexities will hopefully support more
effective HIV prevention and control efforts in the future.
Keywords: Human Immunodeficiency Virus (HIV), Infection, Immunopathogenesis,
Vaccines Mechanism